The evolution of the human brain explains how we got so fat

The evolution of the human brain explains how we got so fatThe evolution of the human brain explains how we got so fatIts strange that we havent come up with a better way of neatly explaining the origin of life to skeptics other than The Big Bang. For one thing, the term welches coined somewhat in jest by one of the theorys staunchest detractors. During a 1949 BBC radio broadcast, astronomer Fred Hoyle (who was all about the continuous expansion theory) was the first to utter the moniker, in an attempt to illustrate how implausible the whole thing was, yet to this day, academicians and civilians alike privilege the title over all others. Whats more, as many have already pointed out, the name actually does a disservice to the content of the theory, with Big implying size even though space wasnt a thing when it occurred-technically speaking, and there wasnt actually a Bang.The popularity of the pet name neither breaks my leg nor picks my pocket, but it does seem to roll off the tongues of dense-talking-snake-enthusiasts with irritating ease. I mostly feel bad for the people that dedicate their lives to relevant breakthroughs breakthroughs that sometimes offer only a single clue to the most pressing Who Done It? case of all time. Its an exciting thing to watch from the sidelines, thousands of cosmologist, physicists and podcast hosts eagerly lining up to add one more pixel to a canvas that is dispiritingly closer to being vacant than it is to being completed. I recall physicist and director of the NASA Institute for Universal Biology, Nigel Goldenfeld,who applied physics and aufstrebend states of matter to an equation that is usually only discussed in biological terms.Follow Ladders on FlipboardFollow Ladders magazines on Flipboard covering Happiness, Productivity, Job Satisfaction, Neuroscience, and moreEvery once in awhile pioneering research on the subject is less about populating the frame and more about acquiring the tools to make a new one, as is the case wi th a new report published this year in the jurnal Genome Biology and Evolution.Second only to how did we get here? Is how did we get so fat? Our scrappy simian cousins may only be a chromosome away from us but were worlds apart as far as body fat is concerned. Its not uncommon for a healthy adult human body to be composed of anywhere between 14% to 31% body fat compared to the 9% body fat found on an average chimpanzee. At some point, after humans split with other primates in the evolutionary tapestry, the method in which the former packaged DNA in their fat cells altered drastically. The end result, according to Devi Swain-Lenz, a postdoctoral associate in biology at Duke University and the lead researcher behind the new study, hindered our ability to turn white fat into brown fat.Brown fat vs. White fatWhite adipose tissue (often referred to as white fat) is segmented by two different variations, visceral fat or subcutaneous fat. Visceral fat refers to the white fat stored within the abdominal cavity and located near several vital organs, including the liver, intestines, and stomach while subcutaneous fat is the stuff located just beneath the skin, the stuff that gathers around our waists and gifts us beer bellies, thunder thighs and so forth. White fat like brown fat serves its purpose but an excess of it is a pretty reliable predictor for several serious illnesses. Too much subcutaneous fat will companion traditionally undesirable features, but an increased build-up of visceral fat is the one you have to worry about, as this is the one associated with increased risk for conditions like diabetes, cancer, heart disease, and even depression. Conversely, brown and similarly beige fat, the former of which is primarily found in the upper neck and upper back, helps us burn calories, generate heat and regulate our body temperature. Lean people tend to have a much larger reserve of brown fat than overweight people do, though evolution has collectively curbed our ab ility to fund the conversion.A collection of fat samples abstracted from chimps, humans and rhesusmacaques monkeys was compared by Swain-Lenz and Duke biologist Greg Wray with the help of a technique called ATAC-seq. The researchers noted around 780 DNA regions that had become bunched in humans but were still accessible to the other primate species observed in the study. Upon further inspection, it was revealed that the genomes that better enabled us to convert calorie storing white fat to beige or brown fat were effectively tucked away.Weve lost some of the ability to shunt fat cells toward beige or brown fat, and were stuckverzierung down the white fat pathway. Its still possible to activate the bodys limited brown fat by doing things like exposing people to cold temperatures, but we need to work for it.Swain-Lenz told India Today.The human brain has just about tripled in size since we branched off from the other primates six to eight million years ago. To support this urgent rate of growth, our bodies began to produce more white fat than brown fat, as the human brain requires an exorbitant amount of energy (more than any other tissue in fact.) This fascinating retcon behind why weve become considerably less sinewy than chimps might additionally provide some useful insights into the ever-present obesity crisis, though Swain-Lenz cautions us against holding our breath for a super solution to our obesity problem.Maybe we could figure out a group of genes that we need to turn on or off, but were still very far from that, Swain-Lenz continued. I dont think that its as simple as flipping a switch. If it were, we would have figured this out a long time ago,